FIG. 2.

GAGs inhibit gliding motility. Incubation of parasites with increasing concentrations (6.2, 12.5, and 25 mg/ml) of heparin (Hep), heparan sulfate (HepS), CSA, CSC, and dextran sulfate (DS), but not dextran (D), resulted in a significant inhibition of attachment to serum-coated glass (A) and relative gliding as monitored by the formation of trails (B). Control represents the extent of attachment or gliding in medium lacking additives. The data are reported as average percentages of control plus SE; n = 3.