. Author manuscript; available in PMC: 2024 Apr 25.

Published in final edited form as: Dalton Trans. 2023 Apr 25;52(16):5176–5191. doi: 10.1039/d3dt00059a

Table 3.

EC₅₀ and maximum relaxant effect (Emax) induced by the metal complexes Ru1–5, metal complex precursors and SNP, using isolated aortic rings preparations of rats.

Compound	EC₅₀ [EC_95%] (μmol L⁻¹)	Emax (%)

SNP	0.0009 [0.0007–0.0012]	111.43±3.90%
RuCl₂(bpy)₂	7.5858 [6.6069–8.7096]	56.49±1.31%

2MIM	> 30	29.51±0.98%
ETU	> 30	38.85±0.85%

Ru1	0.1651 [0.1148–0.2363]	98.80±1.98%
Ru2	0.4645 [0.3766–0.5723]	112.83±2.18%
Ru3	0.1982 [0.1477–0.2651]	112.22±2.23%
Ru4	0.0950 [0.0759–0.1187]	110.91±1.49%
Ru5	0.2288 [0.1765–0.2964]	111.23±2.53%