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. 2023 May 8;45(3):400–408. doi: 10.1097/FTD.0000000000001043

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Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology.

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FIGURE 3. — ATV accumulation experiment represented in percentage of accumulation from the control condition (ATV accumulation in HEK_CTRL at the lowest concentration) in (A) single transfectant HEK_OATP2B1WT versus double transfectant HEK_{OATP2B1WT-MRP1WT} and versus HEK_CTRL (*P < 0.05, ****P < 0.0001 compared with double transfectant WT model) and in (B) double WT transfectant versus variant models (**P < 0.01, ***P < 0.001, ****P < 0.001 compared with HEK_{OATP2B1var-MRP1WT} model and #####P < 0.0001 compared with HEK_{OATPWT-MRP1var}).