TABLE I.

Rules for Using the 95% CI of the Mean Cytotoxicity to Designate a Substance as Superior or Not to LCC and as Non-Inferior or Not to HCC^*

	Interpretation
Investigation of superiority to LCC
95% CI lower bound >10% cytotoxicity	Superior to LCC
95% CI upper bound <10% cytotoxicity	Non-superior to LCC
95% CI includes 10%	Indeterminate (may or may not be superior to LCC)
Investigation of non-inferiority to HCC
95% CI lower bound >90% cytotoxicity	Non-inferior to HCC
95% CI upper bound <90% cytotoxicity	Inferior to HCC
95% CI includes 90%	Indeterminate (may or may not be non-inferior to HCC)

^*LCC = low-cytotoxicity control, HCC = high-cytotoxicity control.