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[Preprint]. 2023 Apr 24:rs.3.rs-2809973. [Version 1] doi: 10.21203/rs.3.rs-2809973/v1

Table 1:

Baseline and Post-Treatment Cognitive and Functional Status Assessments

Cognitive Test Baseline Mean (SD) Post-Treatment Mean (SD) T-test(df), p-value
MoCA 16.2 (2.9) 16.0 (1.1) t(4)=−0.196, p=0.85
CDR Sum of Boxes 5.30 (2.2) 5.60 (2.0) t(4)=2.449, p=0.070
HVLT-R Immediate Total Recall 13.80 (4.4) 10.20 (4.6) t(4)=−3.674, p=0.021*
HVLT-R Delayed Recall 0.60 (0.9) 0.40 (0.9) t(4)=−1.000, p=0.37
WMS Logical Memory Immediate Recall 12.6 (6.5) 13.2 (1.9) t(4)=0.220, p=0.84
WMS Logical Memory Delayed Recall 14.2 (2.2) 12.0 (2.8) t(4)=−1.633, p=0.18
Benson Figure Copy 8.60 (6.2) 14.6 (2.5) t(4)=2.390, p=0.075
Benson Figure Delayed Recall 0.80 (1.5) 2.50 (3.1) t(4)=2.049, p=0.13
Number Span Forward 6.40 (1.8) 6.80 (1.6) t(4)=0.784, p=0.48
Number Span Backward 4.60 (1.7) 4.80 (1.3) t(4)=0.343, p=0.75
Trails A, Time to Completion (Seconds) 76.0 (35) 99.0 (71) t(4)=1.137, p=0.32
Trails B, Time to Completion (Seconds) 208 (86) 212 (84) t(4)=0.829, p=0.45
Phonemic Fluency (F,A,S) 32.0 (5.8) 31.4 (5.5) t(4)=−0.187, p=0.86
Semantic Fluency (Animals) 9.80 (1.3) 11.0 (3.2) t(4)=1.124, p=0.32
Lawton IADL 11.0 (4.9) 10.4 (5.3) t(4)=−0.612, p=0.57
GDS-15 4.00 (3.1) 3.60 (2.4) t(4)=−0.459, p=0.67
NPI 5.40 (7.7) 3.80 (4.8) t(4)=−0.758, p=0.49

Note: Baseline to post-treatment changes were assessed using paired samples t-tests. MoCA = Montreal Cognitive Assessment, CDR = Clinical Dementia Rating scale, HVLT-R = Hopkins Verbal Learning Test Revised, WMS = Weschler Memory Scales, Trails = Trail Making Test, IADL = Independent Activities of Daily Living, ADL = Activities of Daily Living, GDS-15 = Geriatric Depression Scale 15-Item, NPI = Neuropsychiatric Inventory,

*

p<0.05