Table 1:
Cognitive Test | Baseline Mean (SD) | Post-Treatment Mean (SD) | T-test(df), p-value |
---|---|---|---|
MoCA | 16.2 (2.9) | 16.0 (1.1) | t(4)=−0.196, p=0.85 |
CDR Sum of Boxes | 5.30 (2.2) | 5.60 (2.0) | t(4)=2.449, p=0.070 |
HVLT-R Immediate Total Recall | 13.80 (4.4) | 10.20 (4.6) | t(4)=−3.674, p=0.021* |
HVLT-R Delayed Recall | 0.60 (0.9) | 0.40 (0.9) | t(4)=−1.000, p=0.37 |
WMS Logical Memory Immediate Recall | 12.6 (6.5) | 13.2 (1.9) | t(4)=0.220, p=0.84 |
WMS Logical Memory Delayed Recall | 14.2 (2.2) | 12.0 (2.8) | t(4)=−1.633, p=0.18 |
Benson Figure Copy | 8.60 (6.2) | 14.6 (2.5) | t(4)=2.390, p=0.075 |
Benson Figure Delayed Recall | 0.80 (1.5) | 2.50 (3.1) | t(4)=2.049, p=0.13 |
Number Span Forward | 6.40 (1.8) | 6.80 (1.6) | t(4)=0.784, p=0.48 |
Number Span Backward | 4.60 (1.7) | 4.80 (1.3) | t(4)=0.343, p=0.75 |
Trails A, Time to Completion (Seconds) | 76.0 (35) | 99.0 (71) | t(4)=1.137, p=0.32 |
Trails B, Time to Completion (Seconds) | 208 (86) | 212 (84) | t(4)=0.829, p=0.45 |
Phonemic Fluency (F,A,S) | 32.0 (5.8) | 31.4 (5.5) | t(4)=−0.187, p=0.86 |
Semantic Fluency (Animals) | 9.80 (1.3) | 11.0 (3.2) | t(4)=1.124, p=0.32 |
Lawton IADL | 11.0 (4.9) | 10.4 (5.3) | t(4)=−0.612, p=0.57 |
GDS-15 | 4.00 (3.1) | 3.60 (2.4) | t(4)=−0.459, p=0.67 |
NPI | 5.40 (7.7) | 3.80 (4.8) | t(4)=−0.758, p=0.49 |
Note: Baseline to post-treatment changes were assessed using paired samples t-tests. MoCA = Montreal Cognitive Assessment, CDR = Clinical Dementia Rating scale, HVLT-R = Hopkins Verbal Learning Test Revised, WMS = Weschler Memory Scales, Trails = Trail Making Test, IADL = Independent Activities of Daily Living, ADL = Activities of Daily Living, GDS-15 = Geriatric Depression Scale 15-Item, NPI = Neuropsychiatric Inventory,
p<0.05