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. 2023 Apr 13;39(5):btad194. doi: 10.1093/bioinformatics/btad194

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Data summary of the EBD. A. EBD includes 889 biomarkers for 26 eye diseases from 1196 studies. We classified these biomarkers according to their components, as 177 nucleic acids-based biomarkers (12 genetic locus biomarkers, 117 DNA, 35 miRNA, 8 mRNA, 1 DNA methylation, 3 lncRNA, and 1 circRNA), 191 protein biomarkers, and 130 metabolite biomarkers. Further, we also include 91 eye measures, 194 image biomarkers, and 106 other biomarkers (including cytokines, blood measures, diseases, symptoms, and therapies). B. For eye as biomarker for systemics diseases, EBD collects 939 eye biomarkers for 181 systemic diseases, from 890 studies.