Table 1.
Demographic and clinical characteristics of study participants
| Elevated IL-6 group, n = 101 | Normal or non-elevated IL-6 group, n = 107 | P value | ||
|---|---|---|---|---|
| Age (year), mean ± SD | 55.57 17.12 |
51.72 15.29 |
0.09 | |
| BMI, mean ± SD | 27.50 4.27 |
27.90 4.73 |
0.52 | |
| Sex, n (%) | Female | 45 (42.5) | 61 (57.5) | 0.07 |
| Male | 56 (54.9) | 46 (45.1) | ||
| HTN, n (%) | No | 73 (47.1) | 82 (52.9) | 0.47 |
| Yes | 28 (52.8) | 25 (47.2) | ||
| DM, n (%) | No | 81 (48.8) | 85 (51.2) | 0.89 |
| Yes | 20 (47.6) | 22 (52.4) | ||
| COPD, n (%) | No | 100 (49.5) | 102 (50.5) | 0.21 |
| Yes | 1 (16.7) | 5 (83.5) | ||
| CVD, n (%) | No | 92 (48.4) | 98 (51.6) | 0.90 |
| Yes | 9 (50) | 9 (50) | ||
| Cancer, n (%) | No | 99 (49.7) | 100 (50.3) | 0.17 |
| Yes | 2 (22.2) | 7 (77.8) | ||
| CRF, n (%) | No | 96 (48.0) | 104 (52.0) | 0.49 |
| Yes | 5 (62.5) | 3 (37.5) | ||
| Autoimmune disease, n (%) | No | 98 (48.0) | 106 (52.0) | 0.29 |
| Yes | 3 (75.0) | 1 (25.0) | ||
| RA, n (%) | No | 92 (47.7) | 101 (52.3) | 0.36 |
| Yes | 9 (60.0) | 6 (40.0) | ||
| Dyslipidemia, n (%) | No | 96 (49.2) | 99 (50.8) | 0.45 |
| Yes | 5 (38.5) | 8 (61.5) | ||
| Asthma, n (%) | No | 95 (49.2) | 98 (50.8) | 0.50 |
| Yes | 6 (40.0) | 9 (60.0) | ||
| SBP, mean ± SD | 132.63 19.83 |
131.32 17.10 |
0.61 | |
| DBP, mean ± SD | 81.59 14.41 |
82.78 9.87 |
0.49 | |
| T, mean ± SD | 36.83 0.69 |
36.60 0.48 |
0.99 | |
| RR, mean ± SD | 20.67 7.16 |
20.58 7.20 |
0.93 | |
| h, mean ± SD | 92.25 18.32 |
92.70 14.11 |
0.84 | |
| O2 SAT, mean ± SD | 89.80 6.28 |
91.60 4.96 |
0.23 | |
| WBC, mean ± SD | 5.99 2.93 |
5.51 2.43 |
0.21 | |
| Neutrophil, mean ± SD | 78.47 8.66 |
77.64 9.67 |
0.54 | |
| NLR, mean ± SD | 4.63 2.74 |
4.94 5.24 |
0.63 | |
| Platelet, mean ± SD | 186.55 71.35 |
198.05 90.60 |
0.32 | |
| AST, mean ± SD | 41.87 24.68 |
43.66 40.38 |
0.71 | |
| ALT, mean ± SD | 39.37 35.10 |
40.95 36.13 |
0.75 | |
| CRP, mean ± SD | 73.91 54.30 |
74.97 49.92 |
0.93 | |
BMI: Body mass index; HTN: Hypertension; DM: Diabetes mellitus; COPD: Chronic obstructive pulmonary disease; CVD: Cardiovascular disease; CRF: Chronic renal failure; RA: Rheumatoid arthritis; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; T: Temperature; RR: Respiratory rate; HR: Heart rate; NLR: Neutrophil to lymphocyte ratio; AST: Aspartate aminotransferase; ALT: alanine transaminase; CRP: C-reactive protein