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. 2023 May 9;20:27. doi: 10.1186/s12981-023-00517-z

Table 3.

Factors associated with psychosocial impact categories, DC Cohort 2020–2021

Financial/employmenta
(n = 690)
Mental healthb
(n = 690)
Decreased social connectionc
(n = 690)
Increased substance used
(n = 626)
aOR (95%CI) P-value aOR (95%CI) P-value aOR (95%CI) P-value aOR (95%CI) P-value
Age (continuous), per 10 year increase 0.76 (0.63–0.90) 0.0022 0.72 (0.58–0.89) 0.0031 0.77 (0.64–0.91) 0.0030 0.72 (0.56–0.92) 0.0094
Gender identity
 Male Ref. Ref. Ref. Ref.
 Female 0.83 (0.53–1.31) 0.4302 1.03 (0.61–1.74) 0.9208 1.04 (0.66–1.62) 0.8765 0.40 (0.19–0.83) 0.0144
Race/ethnicity
 Non-Hispanic White Ref. Ref. Ref. Ref.
 Non-Hispanic Black 1.43 (0.88–2.33) 0.1532 0.64 (0.32–1.19) 0.1723 0.42 (0.25–0.70) 0.0010 0.62 (0.34–1.13) 0.1145
Hispanic, any race 1.43 0.66–3.18) 0.3684 6.00 (1.12–111.33) 0.0907 0.26 (0.12–0.58) 0.0011 0.64 (0.23–1.67) 0.3722
Other (American Indian/Alaska native, Asian, Native Hawaiian/Pacific Islander, Bi/multiracial) 1.11 (0.49–2.50) 0.8083 0.62 (0.22–1.84) 0.3669 0.25 (0.11–0.58) 0.0011 0.56 (0.19–1.52) 0.2725
Education
 At least some high school Ref. Ref. Ref. Ref.
 At least some college 0.59 (0.41–0.85) 0.0043 1.82 (1.19–2.81) 0.0061 1.54 (1.08–2.19) 0.0167 3.31 (1.87–6.15)  < 0.0001
Self-reported underlying medical conditions
 0 Ref. Ref. Ref. Ref.
 ≥ 1 1.10 (0.73–1.64) 0.6595 1.56 (0.96–2.52) 0.0713 1.32 (0.88–1.97) 0.1775 0.98 (0.58–1.67) 0.9280
Survey year
 2021 Ref. Ref. Ref. Ref.
 2020 1.34 (0.85–2.14) 0.2141 1.60 (0.91–2.97) 0.1159 1.84 (1.17–2.93) 0.0095 1.23 (0.64–2.26) 0.5209
Length of diagnosis (per year) 1.00 (0.98–1.02) 0.7387 1.00 (0.98–1.02) 0.9133 1.00 (0.98–1.02) 0.8933 0.99 (0.96–1.02) 0.4569
AIDS CD4 ≥ 200 cells/ml vs. < 200 (Ref.) 1.29 (0.50–3.26) 0.5911 0.41 (0.09–1.39) 0.1915 0.52 (0.21–1.25) 0.1495 0.86 (0.29–2.82) 0.7856
Suppressed HIV RNA < 200 copies/ml vs > 200 (Ref.) 0.48 (0.23–0.97) 0.0476 0.80 (0.30–1.89) 0.6308 1.50 (0.78–2.91) 0.2242 0.48 (0.22–1.06) 0.0616
HIV mode of transmission
 MSM Ref. Ref. Ref. Ref.
 Hetero 0.93 (0.55–1.56) 0.7702 0.90 (0.49–1.67) 0.7397 0.85 (0.50–1.42) 0.5218 2.03 (0.94–4.33) 0.0688
 IDU 1.27 (0.58–2.83) 0.5446 1.45 (0.59–3.86) 0.4332 1.02 (0.47–2.22) 0.9594 2.04 (0.53–6.54) 0.2571
 Other 1.60 (1.00–2.57) 0.0493 1.14 (0.65–2.03) 0.6624 0.92 (0.58–1.45) 0.7150 0.80 (0.39–1.54) 0.5183

aReported at least 1 of the following: Household income decreased, Lost health insurance, Lost housing, Negative impact on paying rent/mortgage, Negative impact on getting food

bReported at least 1 of the following: Quality of life decreased, Feeling anxious increased, Quality of sleep decreased, PHQ-2 positive (both questions answered affirmatively)

cReported at least 1 of the following: Feeling connected to family decreased, Feeling connected to friends decreased

dReported at least 1 of the following: Use of illicit drugs increased; Use of alcohol increased