Table 2.
The association of CCI components and severe COVID-19 in a multivariate logistic regression model
| Diseases (Abbr. %) | All COVID-19 cases (N = 20,320) | Non-severe COVID-19 (N = 19,033) | Severe COVID-19 (N = 1,287) | OR (95% CI)* | P-Value* |
|---|---|---|---|---|---|
| Myocardial infarction (MI, %) | 663 (3.3%) | 523 (2.7%) | 140 (10.9%) | 4.32 (3.55, 5.25) | < 0.001 |
| Congestive heart-failure (CHF, %) | 309 (1.5%) | 208 (1.1%) | 101 (7.8%) | 7.71 (6.03, 9.85) | < 0.001 |
| Peripheral vascular disease (PVD, %) | 418 (2.1%) | 303 (1.6%) | 115 (8.9%) | 6.07 (4.85, 7.58) | < 0.001 |
| Cerebrovascular disease (CVD, %) | 585 (2.9%) | 434 (2.3%) | 151 (11.7%) | 5.70 (4.69, 6.92) | < 0.001 |
| Dementia (%) | 120 (0.6%) | 79 (0.4%) | 41 (3.2%) | 7.85 (5.39, 11.56) | < 0.001 |
| Chronic pulmonary disease (CPD, %) | 2,040 (10.0%) | 1,755 (9.2%) | 285 (22.1%) | 2.80 (2.43, 3.22) | < 0.001 |
| Rheumatic diseases (Rh, %) | 356 (1.8%) | 289 (1.5%) | 67 (5.2%) | 3.56 (2.71, 4.68) | < 0.001 |
| Peptic ulcer disease (PUD, %) | 423 (2.1%) | 361 (1.9%) | 62 (4.8%) | 2.62 (1.99, 3.45) | < 0.001 |
| Mild liver disease (MLD, %) | 326 (1.6%) | 257 (1.4%) | 69 (5.4%) | 4.14 (3.15, 5.43) | < 0.001 |
| Diabetes (DM, %) | 1,149 (5.7%) | 895 (4.7%) | 254 (19.7%) | 4.98 (4.28, 5.81) | < 0.001 |
| Hemiplegia/Paraplegia | 144 (0.7%) | 103 (0.5%) | 41 (3.2%) | 6.05 (4.19, 8.72) | < 0.001 |
| Moderate or severe renal disease (SRD, %) | 356 (1.8%) | 242 (1.3%) | 114 (8.9%) | 7.55 (5.99, 9.50) | < 0.001 |
| Diabetes with end-organ damage (DMD, %) | 115 (0.6%) | 73 (0.4%) | 42 (3.3%) | 8.76 (5.97, 12.86) | < 0.001 |
| Any malignant tumor (MT, %) | 1,387 (6.8%) | 1,214 (6.4%) | 173 (13.4%) | 2.28 (1.92, 2.70) | < 0.001 |
| Moderate or severe liver disease (SLD, %) | 46 (0.2%) | 29 (0.2%) | 17 (1.3%) | 8.77 (4.81, 16.01) | < 0.001 |
| Metastatic solid tumor (ST, %) | 206 (1.0%) | 175 (0.9%) | 31 (2.4%) | 2.66 (1.81, 3.91) | < 0.001 |
| AIDS/HIV | 11 (0.1%) | 9 (0.0%) | 2 (0.2%) | 3.29 (0.71, 15.24) | 0.128 |
Abbr Abbreviation, OR odds ratio, CI confidence interval
*P value and OR were estimated in the logistic regression model, adjusted for age, sex, income, and BMI