Table 1. ZikV polyproteins and human MS autoantigens-related proteins.
| ZikV polyproteins | Multiple sclerosis autoantigens |
|---|---|
| Chain B, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain PDB: 5GS6_B |
myelin oligodendrocyte glycoprotein (MOG) UniProtKB- Q16653 |
| Chain A, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain PDB: 5GS6_A |
myelin basic protein (MBP) UniProtKB- P02686 |
| Chain A, Zika Virus Non-structural Protein 1 (ns1) PDB: 5K6K_A |
Myelin associated glycoprotein (MAG) UniProtKB- P20916 |
| Chain B, Zika Virus Non-structural Protein 1 (ns1) PDB: 5K6K_B |
Myelin proteolipid protein (PLP) UniProtKB- P60201 |
| Chain A, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro PDB: 5 × 8Y_A |
|
| Chain B, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro PDB: 5 × 8Y_B |
|
| NS1 [Zika virus] NCBI Reference Sequence: YP_009430301.1 |
|
| NS2a NCBI Reference Sequence: YP_009430302.1 |
|
| NS2b NCBI Reference Sequence: YP_009430303.1 |
|
| NS3 NCBI Reference Sequence: YP_009430304.1 |
|
| NS4a NCBI Reference Sequence: YP_009430305.1 |
|
| NS4b Chain A, Structure of Zika Virus Ns5 NCBI Reference Sequence: YP_009430307.1 |
|
| Chain B, Structure of Zika Virus Ns5 PDB: 5TMH_A |
|
| NS5 protein, partial [Zika virus] GenBank: AJD79051.1, AMP44573.1, AMX81921.1, AMX81921.1 |
|
| envelope protein E, partial [Zika virus] GenBank: AOX24134.1 |
|
| capsid protein C [Zika virus] NCBI Reference Sequence: YP_009430296.1 |