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. 2023 May 9;81(4):357–368. doi: 10.1055/s-0043-1768698

Table 3. Results of alignment between ZikV polyproteins and MS autoantigens.

Autoantigens Polyproteins Identity
MOG NS1 50%
MOG Chain B, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 43%
MOG Chain A, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 43%
MOG Chain A, Zika Virus Non-structural Protein 1 (ns1) 43%
MOG Chain B, Zika Virus Non-structural Protein 1 (ns1) 43%
MOG Chain A, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 36%
MOG Chain B, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 36%
MOG NS2a 0%
MOG NS2b 0%
MOG NS3 67%
MOG NS4a 50%
MOG NS4b 29%
MOG Chain A, Structure of Zika Virus Ns5 50%
MOG Chain B, Structure of Zika Virus Ns5 50%
MOG NS5 protein, partial [Zika virus] 50%
MOG envelope protein E, partial 50%
MOG capsid protein C 35%
PBM Chain B, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 0%
PBM Chain A, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 0%
PBM Chain A, Zika Virus Non-structural Protein 1 (ns1) 0%
PBM Chain B, Zika Virus Non-structural Protein 1 (ns1) 0%
PBM Chain A, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 0%
PBM Chain B, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 0%
PBM NS1 0%
PBM NS2a 50%
PBM NS2b 21%
PBM NS3 33%
PBM NS4a 33%
PBM NS4b 40%
PBM Chain A, Structure of Zika Virus Ns5 32%
PBM Chain B, Structure of Zika Virus Ns5 32%
PBM NS5 protein, partial 30%
PBM envelope protein E, partia 40%
PBM capsid protein C 0%
MAG Chain B, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 0%
MAG Chain A, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 0%
MAG Chain A, Zika Virus Non-structural Protein 1 (ns1) 0%
MAG Chain B, Zika Virus Non-structural Protein 1 (ns1) 0%
MAG Chain A, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 0%
MAG Chain B, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 0%
MAG NS1 0%
MAG NS2a 50%
MAG NS2b 21%
MAG NS3 33%
MAG NS4a 33%
MAG NS4b 40%
MAG Chain A, Structure of Zika Virus Ns5 32%
MAG Chain B, Structure of Zika Virus Ns5 32%
MAG NS5 protein, partial 30%
MAG envelope protein E, partial 40%
MAG capsid protein C 0%
PLP Chain B, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 56%
PLP Chain A, Full-length Ns1 Structure of Zika Virus From 2015 Brazil Strain 56%
PLP Chain A, Zika Virus Non-structural Protein 1 (ns1) 56%
PLP Chain B, Zika Virus Non-structural Protein 1 (ns1) 56%
PLP Chain A, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 0%
PLP Chain B, A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus Ns1 Assembly In Vitro 0%
PLP NS1 56%
PLP NS2a 24%
PLP NS2b 38%
PLP NS3 46%
PLP NS4a 0%
PLP NS4b 50%
PLP Chain A, Structure of Zika Virus Ns5 30%
PLP Chain B, Structure of Zika Virus Ns5 30%
PLP NS5 protein, partial 83%
PLP envelope protein E, partial 42%
PLP capsid protein C 20%