Comparison 8. Varenicline in specific settings/subgroups.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
8.1 Hospital inpatients/perioperative patients	6	1324	Risk Ratio (M‐H, Fixed, 95% CI)	1.27 [1.12, 1.43]
8.2 Smokers with a previous quit attempt on varenicline	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
8.3 Light or heavy smokers	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
8.3.1 Light smokers	2	114	Risk Ratio (M‐H, Fixed, 95% CI)	4.16 [1.58, 10.97]