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Reported Substitutions of Arginine at Codon 98 of the MEN1 Protein and Their Predictions of Functional Effects.
| Nucleotide change (amino acid change) | Source | PolyPhen2 (Score/prediction) | PROVEAN (Score/prediction) |
|---|---|---|---|
| c.293G>C (p.R98P) | This case | 0.995/probably damaging | -4.805/deleterious |
| c.293G>A (p.R98Q) | ClinVar | 0.743/possibly damaging | -2.341/neutral |
| c.293G>T (p.R98L) | Article (1) | 0.966/probably damaging | -4.889/deleterious |
