Table 1.

Prediction accuracy of MS-PRS in the test datasets

MS prevalence	$R_l^2$ (95% CI)
	UKBB2	KPNC
0.00127	7.7 (6.8–8.7)	12.5 (11.5–13.5)
0.0019	8.3 (7.3–9.2)	13.3 (12.3–14.4)
0.0069	10.6 (9.4–11.8)	16.9 (15.7–18.2)

The regression P-values were 3.13 × 10⁻¹⁷⁰ and 1.56 × 10⁻⁵⁷ for UKBB2 and KPNC datasets, respectively. $R_l^2$= coefficient of determination on the liability scale.