Table 2. Comparison of mortality, length of stay, hospital cost and IBD complications between ulcerative colitis patients with and without Helicobacter pylori infection.
Ulcerative colitis without Helicobacter pylori (n=405,491) | Ulcerative colitis with Helicobacter pylori (n=805) | Odds Ratio (CI) | p-value | AOR (CI) | Adjusted p-value | |
Mortality (%) | 33,296 (8.22) | 28 (3.48) | 0.403 (0.276 to 0.588) | <0.05 | 0.33 (0.212 to 0.512) | <0.05 |
IBD-associated arthropathy | 709 (0.17) | 0 (0) | 0.998 (0.998 to 0.998) | 0.235 | n/a | n/a |
Erythema nodosum | 330 (0.08) | 0 (0) | 0.998 (0.998 to 0.998) | 0.418 | n/a | n/a |
Uveitis | 182 (0.04) | 1 (0.12) | 2.77 (0.388 to 19.794) | 0.289 | 2.964 (0.413 to 21.283) | 0.28 |
Primary sclerosing cholangitis | 5,201 (1.28) | 3 (0.37) | 0.288 (0.093 to 0.895) | <0.05 | 0.394 (0.126 to 1.227) | 0.108 |
Lower gastrointestinal bleed | 21,942 (5.4) | 82 (10.19) | 1.983 (1.577 to 2.492) | <0.05 | 1.972 (1.525 to 2.551) | <0.05 |
Bowel obstruction | 8,785 (2.17) | 16 (1.99) | 0.916 (0.558 to 1.503) | 0.728 | 1.073 (0.643 to 1.793) | 0.786 |
Intra-abdominal abscess | 3,608 (0.89) | 1 (0.12) | 0.139 (0.019 to 0.985) | <0.05 | 0.165 (0.023 to 1.175) | 0.072 |
Intestinal perforation | 8,743 (2.16) | 9 (1.12) | 0.513 (0.266 to 0.99) | <0.05 | 0.408 (0.182 to 0.912) | <0.05 |
Ileostomy | 7,600 (1.87) | 9 (1.12) | 0.592 (0.307 to 1.142) | 0.114 | 0.664 (0.315 to 1.4) | 0.282 |
Colostomy | 3,294 (0.81) | 4 (0.49) | 0.61 (0.228 to 1.63) | 0.319 | (0.28 to 2.005) | 0.565 |
Mean Difference (CI) | p-value | AOR (CI) | Adjusted p-value | |||
Mean Length of Stay (SD) | 7.82 days (10.691) | 7.72 (8.573) | 0.109±0.377 (-0.96 to 0.85) | <0.05 | 1.005 (0.997 to 1.013) | 0.256 |
Mean Total Charges (SD) | $65,652.63 (113,213.548) | $47,557.67 (87,006.814) | 18,094.962±4,043.126 (10,170.558 to 26,019.365) | <0.05 | 1 (1-1) | <0.05 |