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. 2023 Apr 9;15(4):e37345. doi: 10.7759/cureus.37345

Table 2. Comparison of mortality, length of stay, hospital cost and IBD complications between ulcerative colitis patients with and without Helicobacter pylori infection.

IBD: inflammatory bowel disease; n: sample size; OR: odds ratio; CI: 95% confidence interval; AOR: adjusted odds ratio; ACI: adjusted confidence interval; n/a: not applicable; SD: standard deviation.

  Ulcerative colitis without Helicobacter pylori (n=405,491) Ulcerative colitis with Helicobacter pylori (n=805) Odds Ratio (CI) p-value AOR (CI) Adjusted p-value
Mortality (%) 33,296 (8.22) 28 (3.48) 0.403 (0.276 to 0.588) <0.05 0.33 (0.212 to 0.512) <0.05
IBD-associated arthropathy 709 (0.17) 0 (0) 0.998 (0.998 to 0.998) 0.235 n/a n/a
Erythema nodosum 330 (0.08) 0 (0) 0.998 (0.998 to 0.998) 0.418 n/a n/a
Uveitis 182 (0.04) 1 (0.12) 2.77 (0.388 to 19.794) 0.289 2.964 (0.413 to 21.283) 0.28
Primary sclerosing cholangitis 5,201 (1.28) 3 (0.37) 0.288 (0.093 to 0.895) <0.05 0.394 (0.126 to 1.227) 0.108
Lower gastrointestinal bleed 21,942 (5.4) 82 (10.19) 1.983 (1.577 to 2.492) <0.05 1.972 (1.525 to 2.551) <0.05
Bowel obstruction 8,785 (2.17) 16 (1.99) 0.916 (0.558 to 1.503) 0.728 1.073 (0.643 to 1.793) 0.786
Intra-abdominal abscess 3,608 (0.89) 1 (0.12) 0.139 (0.019 to 0.985) <0.05 0.165 (0.023 to 1.175) 0.072
Intestinal perforation 8,743 (2.16) 9 (1.12) 0.513 (0.266 to 0.99) <0.05 0.408 (0.182 to 0.912) <0.05
Ileostomy 7,600 (1.87) 9 (1.12) 0.592 (0.307 to 1.142) 0.114 0.664 (0.315 to 1.4) 0.282
Colostomy 3,294 (0.81) 4 (0.49) 0.61 (0.228 to 1.63) 0.319 (0.28 to 2.005) 0.565
  Mean Difference (CI) p-value AOR (CI) Adjusted p-value
Mean Length of Stay (SD) 7.82 days (10.691) 7.72 (8.573) 0.109±0.377 (-0.96 to 0.85) <0.05 1.005 (0.997 to 1.013) 0.256
Mean Total Charges (SD) $65,652.63 (113,213.548) $47,557.67 (87,006.814) 18,094.962±4,043.126 (10,170.558 to 26,019.365) <0.05 1 (1-1) <0.05