1. Antidepressant dose categorisation.
| Antidepressant | Total daily dosage | ||
| Low | Standard | High | |
| Amitriptyline | < 25 mg | 25‐75 mg | > 75 mg |
| Bupropion | n/aa | 150‐300 mg | > 300 mg |
| Citalopram | < 20 mg | 20 mg | 40 mg |
| Clomipramine | < 30 mg | 30‐150 mg | > 150 mg |
| Desipramine | < 100 mg | 100‐200 mg | > 200 mg |
| Desvenlafaxine | n/ab | 50 mg | > 50 mg |
| Dothiepin (dosulepin) | < 75 mg | 75‐150 mg | > 150 mg |
| Doxepin | < 75 mg | 75‐150 mg | > 150 mg |
| Duloxetine | < 60 mg | 60 mg | > 60 mg |
| Escitalopram | < 10 mg | 10 mg | 20 mg |
| Esreboxetine | n/ac | 4‐8 mg | > 8 mg |
| Fluoxetine | < 20 mg | 20‐40 mg | > 40 mg |
| Imipramine | < 75 mg | 75‐150 mg | > 150 mg |
| Nortriptyline | < 75 mg | 75‐100 mg | > 100 mg |
| Maprotiline | 150 mg | 300 mg | > 300 mg |
| Mianserin | < 30 mg | 30‐40 mg | > 40 mg |
| Milnacipran | < 100 mg | 100 mg | > 100 mg |
| Mirtazapine | < 30 mg | 30 mg | > 30 mg |
| Moclobemide | 150 mg | 300 mg | 600 mg |
| Paroxetine | < 20 mg | 20 mg | 50 mg |
| Pirlindole | < 225 mg | 225‐300 mg | > 300 mg |
| Reboxetine | < 8 mg | 8 mg | > 8 mg |
| Sertraline | n/ad | 50 mg | > 50 mg |
| Trazodone | < 150 mg | 150‐300 mg | > 300 mg |
| Trimipramine | < 75 mg | 75‐150 mg | > 150 mg |
| Venlafaxine | < 75 mg | 75‐150 mg | > 150 mg |
| Zimelidine | < 300 mg | 300 mg | > 300 mg |
aLowest dose form is 150 mg.
bDesvenlafaxine is not available in UK, lowest dose form is 50 mg.
cEsreboxetine is not available in UK, and no doses lower than 4 mg have been used in trials.
d50 mg is both the initial and standard dose, no recommendations of lower doses in the British National Formulary.