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. 2023 May 10;2023(5):CD014682. doi: 10.1002/14651858.CD014682.pub2

11. Overview of all interventions in the moderate pain relief analysis.

Treatment RCTs Participants
Antidepressants with ≥ 200 participants
Duloxetine 24 4562
Esreboxetine 2 965
Milnacipran 7 1928
Mirtazapine 2 238
Antidepressants with < 200 participants (excluded from summaries)
Amitriptyline 2 80
Desipramine 1 37
Desipramine + cognitive behavioural therapy 1 37
Imipramine 2 113
Imipramine + pregabalin 1 69
Venlafaxine 1 86
Non‐antidepressant interventions (excluded from summaries)
Carbamazepine 2 85
Cognitive behavioural therapy 2 53
Gabapentin 1 22
Pregabalin 4 680
Terbutaline 1 39
RCT: randomised controlled trial
Participant numbers reflect the total number of participants receiving the antidepressant.