Skip to main content
. 2023 May 10;2023(5):CD014682. doi: 10.1002/14651858.CD014682.pub2

Ozerbil 2006.

Study characteristics
Methods Design: cross‐over
Duration: 2 weeks
Assessment: baseline and post‐intervention
Country: Turkey
Participants Pain condition: fibromyalgia
Population: adult women aged 20‐60 with fibromyalgia
Minimum pain intensity: no
Inclusion criteria
  • Aged 20‐60

  • Fibromyalgia according to ACR classification


Exclusion criteria
  • Current or past history of systemic illness, including cardiac, renal, haematologic, or hepatic disease


Total participants randomised: 15
Age in years (mean, SD): NR
Gender: 15/15 were female
Pain duration in years (mean, SD): NR
Interventions Amitriptyline 25 mg + placebo
  • TCA + placebo

  • Fixed dose

  • Double‐dummy design


Fluoxetine 20 mg + placebo
  • SSRI + placebo

  • Fixed dose

  • Double‐dummy design

Outcomes The study provided no useable data
Missing data methods NR
Funding source NR
Conflicts of interest NR
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Participants were randomised using randomisation tables
Allocation concealment (selection bias) Unclear risk Allocation procedure not specified
Blinding of participants and personnel (performance bias)
All outcomes Low risk Double‐blind, dummy dosing technique and identical tablets
Blinding of outcome assessment (detection bias)
All outcomes Low risk Researcher blinding ‐ not enough information
Incomplete outcome data (attrition bias)
All outcomes Unclear risk No information regarding missing data or withdrawal given
Selective reporting (reporting bias) Unclear risk No protocol or trial registration found
Other bias Low risk No other sources of bias identified