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. 2023 May 10;2023(5):CD014682. doi: 10.1002/14651858.CD014682.pub2

Sencan 2004.

Study characteristics
Methods Design: parallel
Duration: 6 weeks
Assessment: baseline, post‐intervention, follow‐up (6 months)
Country: Turkey
Participants Pain condition: fibromyalgia
Population: women aged 18‐50 with fibromyalgia
Minimum pain intensity: no
Inclusion criteria
  • fibromyalgia patients between ages 18–50, diagnosed by the ACR criteria


Exclusion criteria
  • Physical health comorbidities


Total participants randomised: 60
Age in years (mean): 34.5
Gender: 60/60 were female
Pain duration in years (mean): 5.4
Interventions Aerobic exercise
  • n = 20

  • Aerobic exercises 3 times a week for 6 weeks, each exercise period lasted for 40 minutes


Paroxetine 20 mg
  • n = 20

  • SSRI

  • Fixed dose


Placebo TENS
  • n = 20

  • Placebo TENS with electrodes applied on the 2 most painful tender points for 20 minutes, 3 times a week for 6 weeks

Outcomes Pain intensity
Mood
Missing data methods No participants withdrew
Funding source NR
Conflicts of interest NR
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Randomisation methods not specified
Allocation concealment (selection bias) Unclear risk Allocation procedures not specified
Blinding of participants and personnel (performance bias)
All outcomes High risk Participants unable to be blinded due to the nature of interventions
Blinding of outcome assessment (detection bias)
All outcomes High risk Self‐reported outcomes from unblinded participants
Incomplete outcome data (attrition bias)
All outcomes Low risk No participants withdrew during the trial period
Selective reporting (reporting bias) Unclear risk No protocol or trial registration found
Other bias Low risk No other sources of bias were identified