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. 2023 May 10;2023(5):CD014682. doi: 10.1002/14651858.CD014682.pub2

Zakerkish 2017.

Methods Double‐blind, placebo‐controlled, parallel, 2‐arm RCT
6 weeks
Participants Patients with diabetic peripheral neuropathy
n = 134
Interventions Duloxetine 30‐60 mg
Placebo
Outcomes Pain intensity
50% pain relief
AEs
Notes Unable to establish pain duration, unclear if chronic

AE: adverse event; BPI: Brief Pain Inventory; IASP: International Association for the Study of Pain; LANSS: Leeds Assessment of Neuropathic Symptoms and Signs; NRS: numeric rating scale; OA: osteoarthritis; PGIC: Patient Global Impression of Change; RCT: randomised controlled trial; VAS: visual analogue scale; WOMAC: Western Ontario and McMaster Universities Osteoarthritis pain scale