NCT03249558.

Study name	Effect of combined morphine and duloxetine on chronic pain
Methods	Double‐blind, combination + double‐dummy, parallel, 3‐arm RCT 10 weeks
Participants	18‐70 years old Chronic neck or back pain for at least 3 months VAS ≥ 5 Target: 135
Interventions	Morphine 60 mg + duloxetine 60 mg Morphine 60 mg + placebo Duloxetine 60 mg + placebo
Outcomes	Opioid dose Pain intensity
Starting date	01 February 2018
Contact information	Karina de Sousa kdesousa1@mgh.harvard.edu
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