Reckziegel 2017.

Study name	Imaging pain relief in osteoarthritis (IPRO): protocol of a double‐blind randomised controlled mechanistic study assessing pain relief and prediction of duloxetine treatment outcome
Methods	Double‐blind, placebo‐controlled, parallel, 2‐arm RCT
Participants	Chronic knee pain with radiographically defined OA changes (Kellgren Lawrence ≥ grade 2) Aged ≥ 35 n = 77
Interventions	Duloxetine 60 mg Placebo
Outcomes	Experimental pain Functional magnetic resonance imaging
Starting date	December 2014
Contact information	University of Nottingham ‐ School of Medicine ‐ Radiological Sciences Nottingham, Nottinghamshire, United Kingdom, NG7 2UH
Notes