Table 5.

Association of Race With Estimated Glomerular Filtration Rate (eGFR) Stage Transitions Defined With and Without eGFR Race Coefficient

CKD Progression by eGFR Stage	HR for Black vs White Race (95% CI)
	2009 CKD-EPI eGFRcr Equation	Race-Free 2021 CKD-EPI eGFRcr Equation
Stage 1 to 2	0.77 (.73–.82)	1.37 (1.30–1.45)
Stage 2 to 3	1.00 (0.92–1.07)	1.07 (.99–.16)
Stage 3 to 4	3.06 (2.60–3.62)	1.71 (1.45–2.02)

Abbreviations: CI, confidence interval; CKD, chronic kidney disease; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate; eGFRcr, eGFR creatinine; HR, hazard ratio.

Models adjusted for calendar period (2005–2009 and 2010–2015), age, sex, history of AIDS, hepatitis C, diabetes, hypertension, cardiovascular disease, baseline human immunodeficiency virus viral load, and baseline eGFR. eGFR stages were defined as follows: stage 1, eGFR ≥90 mL/min/1.73 m²; stage 2, 60–89 mL/min/1.73 m²; stage 3, 30–59 mL/min/1.73 m²; and stage 4, <30 mL/min/1.73 m².