Table 1.
Characteristics of Postmenopausal Women in the Women’s Interagency HIV Study at the Baseline Vascular Substudy Visit, by Ever Use of Hormone Therapya
| HT Use | ||||
|---|---|---|---|---|
| Characteristic | Overall (N = 609) |
Never (n = 466) |
Ever (n = 143) |
P Valueb |
| No. of prior visits with HT data, mean (SD) | 9.55 (4.98) | 10.06 (5.17) | 7.90 (3.88) | <.001 |
| Age, y, mean (SD) | 50.93 (5.44) | 50.58 (5.26) | 52.08 (5.89) | .001 |
| HIV positive | 487 (80.0) | 369 (79.2) | 118 (82.5) | .45 |
| Race/ethnicity | <.001 | |||
| ȃBlack non-Hispanic | 378 (62.1) | 299 (64.2) | 79 (55.2) | |
| ȃWhite non-Hispanic | 71 (11.7) | 40 (8.6) | 31 (21.7) | |
| ȃHispanic | 144 (23.6) | 114 (24.5) | 30 (21.0) | |
| ȃOther/missing | 16 (2.6) | 13 (2.8) | 3 (2.1) | |
| Annual income | .06 | |||
| ȃ$12 000 or less | 362 (59.4) | 290 (62.2) | 72 (50.3) | |
| ȃ$12 001–$24 000 | 122 (20.0) | 87 (18.7) | 35 (24.5) | |
| ȃ$24 001–$36 000 | 61 (10.0) | 46 (9.9) | 15 (10.5) | |
| ȃ$36 001 or more | 64 (10.5) | 43 (9.2) | 21 (14.7) | |
| Educational attainment | .04 | |||
| ȃLess than high school | 229 (37.6) | 188 (40.3) | 41 (28.7) | |
| ȃCompleted high school | 199 (32.7) | 151 (32.4) | 48 (33.6) | |
| ȃSome college | 144 (23.6) | 102 (21.9) | 42 (29.4) | |
| ȃCompleted college | 37 (6.1) | 25 (5.4) | 12 (8.4) | |
| Employed | 180 (29.6) | 129 (27.7) | 51 (35.7) | .09 |
| Smoking status | .03 | |||
| ȃNever smoker | 111 (18.2) | 80 (17.2) | 31 (21.7) | |
| ȃCurrent smoker | 311 (51.1) | 252 (54.1) | 59 (41.3) | |
| ȃFormer smoker | 187 (30.7) | 134 (28.8) | 53 (37.1) | |
| Current drinking status | .70 | |||
| ȃAbstainer | 364 (59.8) | 282 (60.5) | 82 (57.3) | |
| ȃ>0–7 drinks/wk | 187 (30.7) | 139 (29.8) | 48 (33.6) | |
| ȃ>7 drinks/wk | 58 (9.5) | 45 (9.7) | 13 (9.1) | |
| Current drug use | 138 (22.7) | 109 (23.4) | 29 (20.3) | .51 |
| HCV positive | 307 (50.4) | 244 (52.4) | 63 (44.1) | .10 |
| BMI, kg/m2, mean (SD) | 28.80 (7.34) | 28.75 (7.43) | 28.94 (7.06) | .64 |
| History of hypertension | 290 (47.6) | 220 (47.2) | 70 (49.0) | .79 |
| History of diabetes | 111 (18.2) | 78 (16.7) | 33 (23.1) | .11 |
| History of CVD | 67 (11.0) | 50 (10.7) | 17 (11.9) | .82 |
| Current lipid-lowering medication | 32 (5.3) | 26 (5.6) | 6 (4.2) | .66 |
| Current HIV viral loadc, copies/mL, geometric mean (SD) | 368.7 (24.3) | 350.7 (27.4) | 437.0 (16.3) | .72 |
| Current detectable HIV viral loadc | 253 (52.0) | 198 (53.7) | 55 (46.6) | .22 |
| Current CD4 countc, cells/µL, mean (SD) | 474.57 (305.98) | 461.25 (309.00) | 516.25 (293.73) | .04 |
| Current ART usec | 368 (75.6) | 276 (74.8) | 92 (78.0) | .57 |
| CIMT, µm, mean (SD) | 791.42 (132.15) | 794.39 (132.79) | 781.74 (130.01) | .23 |
| Carotid artery distensibilityd (10−6 × N–1 × m2), mean (SD) | 15.38 (7.07) | 15.34 (7.08) | 15.50 (7.08) | .85 |
| Presence of carotid artery plaquee | 116 (24.9) | 94 (27.8) | 22 (17.2) | .03 |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: ART, antiretroviral therapy; BMI, body mass index; CIMT, carotid artery intima-media thickness; CVD, cardiovascular disease; HCV, hepatitis C virus; HIV, human immunodeficiency virus; HT, hormone therapy; SD, standard deviation.
Each participant’s first visit in the vascular substudy was used for this summary table.
P values from Wilcoxon rank-sum test or χ2 test for continuous and categorical variables, respectively.
Only in women with HIV (n = 487).
Reduced sample size (n = 531).
Reduced sample size (n = 466).