Figure 2.

Clostridium innocuum culture positivity rates and Ct values from subjects with AAD and asymptomatic controls. A, B, Percentage of CI culture positivity rates for a cohort of subjects with (A) diarrhea (Di) or asymptomatic controls (As), and (B) subjects with diarrhea who are either C. difficile colonized (Di-CDC) or C. difficile negative (Di-CDN). C, D, Box plots of CI Ct values as determined by qPCR of (C) As and Di subjects and (D) As, Di-CDC, and Di-CDN subjects. Boxes show the median and 25th and 75th percentiles. The whiskers represent the maximum and minimum data values. *P < .05 (or Bonferroni-corrected P < .25 for pairwise comparisons of multiple groups in panels B and D); **P < .01; ***P < .001. Abbreviations: AAD, antibiotic-associated diarrhea; CI, Clostridium innocuum; Ct, cycle threshold; ns, not significant; qPCR, quantitative polymerase chain reaction.