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. 2023 Mar 16;37(5):1068–1079. doi: 10.1038/s41375-023-01867-3

Table 1.

Criteria for bone marrow fibrosis grading.

Grading Description
MF-0 no reticulin fibers corresponding to normal bone marrow
MF-0.5 focal areas with a loose network of reticulin with many intersections alternated with areas with no reticulin fibers
MF-1 loose network of reticulin with many intersections evenly distributed over the entire length of the femurs
MF-1.5 focal areas with a diffuse and dense increase in reticulin with extensive intersections
MF-2 diffuse and dense increase in reticulin with extensive intersections evenly distributed over the entire length of the femurs, occasionally with only focal bundles of collagen and/or focal osteosclerosis
MF-3 diffuse and dense increase in reticulin with extensive intersections with coarse bundles of collagen, often associated with significant osteosclerosis