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. 2023 Apr 26;13:1126576. doi: 10.3389/fonc.2023.1126576

Table 3.

CONUT scores and some clinicopathological factors are correlated.

Total CL group,
n (%)
CH group,
n (%)
χ² P value
Age 0.08 0.78
<60.5 607 (77.3%) 314 (77.72%) 293 (76.90%)
≥60.5 178 (22.7%) 90 (22.28%) 88 (23.10%)
BMI (kg/m2) 8.07 0.00
<20.0 33 (4.2%) 9 (2.23%) 24 (6.30%)
≥20.0 752 (95.8%) 395 (97.77%) 357 (93.70%)
Menopause 1.09 0.30
no 319 (40.6%) 157 (38.86%) 162 (42.52%)
yes 466 (59.4%) 247 (61.14%) 219 (57.48%)
Relapse 1.02 0.31
no 774 (98.6%) 400 (99.01%) 374 (98.16%)
yes 11 (1.4%) 4 (0.99%) 7 (1.84%)
PNI 87.73 0.00
<52.83 478 (60.9%) 182 (45.05%) 296 (77.69%)
≥52.8 307 (39.1%) 222 (54.95%) 85 (22.31%)
NLR 44.03 0.00
<1.9 299 (38.1%) 199 (49.26%) 100 (26.25%)
≥1.9 486 (61.9%) 205 (50.74%) 281 (73.75%)
PLR 93.59 0.00
<175.0 627 (79.9%) 377 (93.32%) 250 (65.62%)
≥175.0 158 (20.1%) 27 (6.68%) 131 (34.38%)
LMR 49.36 0.00
<6.45 452 (57.6%) 184 (45.54%) 268 (70.34%)
≥6.45 333 (42.4%) 220 (54.46%) 113 (29.66%)
CA199 (U/ml) 0.48 0.82
<27 351 (67.5%) 175 (67.05%) 176 (67.95%)
≥27 169 (32.5%) 86 (32.95%) 83 (32.05%)
CA125 (U/ml) 1.52 0.22
<35 516 (85.7%) 271 (87.42%) 245 (83.90%)
≥35 86 (14.3%) 39 (12.58%) 47 (16.10%)
CEA (ng/L) 0.71 0.40
<5 513 (98.8%) 260 (99.24%) 253 (98.44%)
≥5 6 (1.2%) 2 (0.76%) 4 (1.56%)
Pathological classification 0.26 0.61
type I 719 (91.6%) 372 (92.08%) 347 (91.08%)
type II 66 (8.4%) 32 (7.92%) 34 (8.92%)
Surgical staging 6.63 0.09
I 607 (77.3%) 321 (79.45%) 286 (75.07%)
II 98 (12.5%) 46 (11.39%) 52 (13.65%)
III 63 (8.0%) 33 (8.17%) 30 (7.87%)
IV 17 (2.2%) 4 (0.99%) 13 (3.41%)
Degree of differentiation 7.46 0.02
G1 437 (55.7%) 243 (60.15%) 194 (50.92%)
G2 263 (33.5%) 125 (30.94%) 138 (36.22%)
G3 85 (10.8%) 36 (8.91%) 49 (12.86%)
Lymphatic vascular space infiltration 1.69 0.19
no 613 (78.1%) 323 (79.95%) 290 (76.12%)
yes 172 (21.9%) 81 (20.05%) 91 (23.88%)
Parastatal infiltration 1.57 0.21
no 753 (95.9%) 391 (96.78%) 362 (95.01%)
yes 32 (4.1%) 13 (3.22%) 19 (4.99%)
Infiltration of muscle layer 5.99 0.01
< 1/2 585 (74.5%) 316 (78.22%) 269 (70.60%)
≥1/2 200 (25.5%) 88 (21.78%) 112 (29.40%)
Cervical interstitial infiltration 1.33 0.25
no 673 352(87.13%) 321 (84.25%)
yes 112 52 (12.87%) 60 (15.75%)
Aortic lymph node metastasis 0.15 0.70
no 772 (98.3%) 398 (98.51%) 374 (98.16%)
yes 13 (1.7%) 6 (1.49%) 7 (1.84%)
Pelvic lymph node metastasis 0.34 0.85
no 747 (95.2%) 385 (95.30%) 362 (95.01%)
yes 38 (4.8%) 19 (4.70%) 19 (4.99%)

CH, CONUT-high; CL, CONUT-low; BMI, body mass index; PNI, prognostic nutrition index; NLR, neutrophil/lymphocyte ratio; PLR=platelet/lymphocyte ratio; LMR, lymphocyte to monocyte ratio; CA199, cancer antigen 199; CA125, cancer antigen 125; CEA, Carcinoembryonic Antigen. Bold and highlighted for significant p-values.