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. 2023 May 10;45(3):1967–1985. doi: 10.1007/s11357-023-00805-6

Table 2.

Clusters with a significant increase (T6-T0) in connectivity with the Hippocampus

Model Cluster size p-FDR peak p-unc Anatomical area Covering
x, y, z Size % Voxels
1 (PE vs. PC) -50, -64, 36 376 0.008716 0.000004 Lateral Occipital Cortex, superior division Left 60 225
Angular Gyrus Left 38 141
Not Labelled 3 10
-30, -70, 22 215 0.046003 0.000003 Lateral Occipital Cortex, superior division Left 33 71
Angular Gyrus Left 4 8
Not Labelled 63 136
2 (PE&CT vs. PE&CTc vs. PC) -50, -64, 32 535 0.0003 0.000008 Lateral Occipital Cortex, superior division Left 57 303
Angular Gyrus Left 16 87
Not Labelled 27 145

  Post-hoc for 2

  (PE&CTc vs. PC)

-50, -64, 44 265 0.035973 0.000023 Lateral Occipital Cortex, superior division Left 60 158
Angular Gyrus Left 37 98
Not Labelled 3 9

  Post-hoc for 2

   (PE&CT vs. PC)

-30, -72, 20 334 0.003614 0.000002 Lateral Occipital Cortex, superior division Left 53 177
Angular Gyrus Left 7 25
Not Labelled 40 132
4 (SYN vs. PC) -38, -60, 32 381 0.001073 0.000007 Lateral Occipital Cortex, superior division Left 51 194
Angular Gyrus Left 10 38
Not Labelled 39 149
4L (SYN vs. PC) -46, -66, 42 297 0.00562 0.000012 Lateral Occipital Cortex, superior division Left 84 248
Not Labelled 16 49

All from the seed-voxel analysis. With the exception of model 4L, the significant clusters within each model demonstrated increased connectivity with the right Hippocampus. c control; CT cognitive training; PC pure control; PE physical exercise; SYN synergic; VD vitamin D; vs. versus