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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: J Hepatol. 2022 Nov 12;78(2):247–259. doi: 10.1016/j.jhep.2022.10.034

Fig. 3. Percentage of patients in rule-out (<85% sensitivity cut-off), indeterminate and rule-in zones (≥90% specificity cut-off) for the diagnosis of cirrhosis with FIB-4, LSM and Agile 4.

Fig. 3.

(A) Training set (n = 1,434), (B) Internal validation set (n = 700), (C) NASH CRN cohort (n = 585), (D) French NAFLD cohort (n = 1,042). On each bar, the solid and transparent parts represent the percentage of patients with and without cirrhosis according to LB, respectively. FIB-4, fibrosis-4 index; LB, liver biopsy; LSM, liver stiffness measurement; NAFLD, non-alcoholic fatty liver disease; NASH CRN, Non-alcoholic Steatohepatitis Clinical Research Network.