FIGURE 2.

Far upstream element‐binding protein 1 (FUBP1) conferred lobaplatin resistance in osteosarcoma in vitro. (A) Western blotting analysis of cleaved caspase 3 and cleaved poly (ADP‐ribose) polymerase (PARP) in the indicated cells; α‐tubulin was used as a loading control. (B) Colony formation assays were used to determine the proliferation ability of the indicated cells. Representative images and quantification are shown. (C) CCK‐8 assays were performed to determine the viabilities of the indicated cells. Cells without any treatment were considered the control. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. shRNA‐V, scrambled shRNA.