Table 1.
Clinical and demographic data for 5355 patients (patients with missing covariate values included)
| Variables | No defunctioning stoma (n = 991) | Defunctioning stoma (n = 4364) | Overall (n = 5355) |
|---|---|---|---|
| Sex | |||
| Male | 504 (50.9) | 2624 (60.1) | 3128 (58.4) |
| Female | 487 (49.1) | 1740 (39.9) | 2227 (41.6) |
| Age (years), median (i.q.r.) | 68 (60–73) | 66 (59–72) | 66 (59–72) |
| BMI (kg/m2), median (i.q.r.) | 25.5 (23.2–28.7) | 25.5 (23.3–28.1) | 25.5 (23.3–28.1) |
| Missing | 51 (5.1) | 149 (3.4) | 200 (3.7) |
| ASA fitness grade | |||
| I | 260 (26.2) | 1134 (26.0) | 1394 (26.0) |
| II | 565 (57.0) | 2561 (58.7) | 3126 (58.4) |
| III | 158 (15.9) | 625 (14.3) | 783 (14.6) |
| Missing | 8 (0.8) | 44 (1.0) | 52 (1.0) |
| Clinical tumour category | |||
| cT1–cT2 | 333 (33.6) | 1101 (25.2) | 1434 (26.8) |
| cT3 | 437 (44.1) | 2494 (57.1) | 2931 (54.7) |
| cT4 | 65 (6.6) | 535 (12.3) | 600 (11.2) |
| cTx | 113 (11.4) | 206 (4.7) | 319 (6.0) |
| Missing | 43 (4.3) | 28 (0.6) | 71 (1.3) |
| Clinical node category | |||
| cN0 | 525 (53.0) | 1766 (40.5) | 2291 (42.8) |
| cN1–cN2 | 328 (33.1) | 2285 (52.4) | 2613 (48.8) |
| cNx | 127 (12.8) | 306 (7.0) | 433 (8.1) |
| Missing | 11 (1.1) | 7 (0.2) | 18 (0.3) |
| Clinical metastasis category | |||
| cM0 | 910 (91.8) | 4043 (92.6) | 4953 (92.5) |
| cM1 | 56 (5.7) | 278 (6.4) | 334 (6.2) |
| cMx | 20 (2.0) | 39 (0.9) | 59 (1.1) |
| Missing | 5 (0.5) | 4 (0.1) | 9 (0.2) |
| Neoadjuvant therapy | |||
| None | 692 (69.8) | 1249 (28.6) | 1941 (36.2) |
| Radiotherapy | 230 (23.2) | 2116 (48.5) | 2346 (43.8) |
| Chemoradiotherapy | 69 (7.0) | 999 (22.9) | 1068 (19.9) |
| Hypertension | 340 (34.3) | 1430 (32.8) | 1770 (33.1) |
| Cardiovascular disease | 82 (8.3) | 364 (8.3) | 446 (8.3) |
| Heart failure | 19 (1.9) | 108 (2.5) | 127 (2.4) |
| Diabetes | 95 (9.6) | 448 (10.3) | 543 (10.1) |
| Chronic obstructive pulmonary disease | 30 (3.0) | 110 (2.5) | 140 (2.6) |
| Surgical technique | |||
| Open | 726 (73.3) | 3576 (81.9) | 4302 (80.3) |
| Laparoscopy | 214 (21.6) | 610 (14.0) | 824 (15.4) |
| Converted to open | 42 (4.2) | 152 (3.5) | 194 (3.6) |
| Missing | 9 (0.9) | 26 (0.6) | 35 (0.7) |
| Anastomotic leakage | 90 (9.1) | 391 (9.0) | 481 (9.0) |
| Healthcare region | |||
| Stockholm-Gotland | 135 (13.6) | 955 (21.9) | 1090 (20.4) |
| Mid-Sweden | 236 (23.8) | 1041 (23.9) | 1277 (23.8) |
| Southeastern | 161 (16.2) | 427 (9.8) | 588 (11.0) |
| Southern | 146 (14.7) | 855 (19.6) | 1001 (18.7) |
| Western | 247 (24.9) | 779 (17.9) | 1026 (19.2) |
| Northern | 66 (6.7) | 307 (7.0) | 373 (7.0) |
| Stage (pathological) | |||
| I | 302 (30.5) | 1278 (29.3) | 1580 (29.5) |
| II | 270 (27.2) | 1169 (26.8) | 1439 (26.9) |
| III | 336 (33.9) | 1553 (35.6) | 1889 (35.3) |
| IV | 63 (6.4) | 295 (6.8) | 358 (6.7) |
| Missing | 20 (2.0) | 69 (1.6) | 89 (1.7) |
| Perioperative bleeding (ml), median (i.q.r.) | 200 (75–400) | 350 (150–600) | 300 (100–600) |
| Missing | 35 (3.5) | 100 (2.3) | 135 (2.5) |
| Tumour height (cm), median (i.q.r.) | 13 (12–14) | 10 (8–12) | 10 (8–13) |
| Missing | 15 (1.5) | 19 (0.4) | 34 (0.6) |
| Hospital volume (operations/year), median (i.q.r.) | 16.8 (12.7–23.6) | 18.7 (13.8–24.9) | 18.4 (13.8–24.9) |
| Operation year, median (i.q.r.) | 2012 (2009–2014) | 2012 (2010–2014) | 2012 (2010–2014) |
Values are n (%) unless otherwise indicated.