Table 1. The baseline characteristics of patients with ccRCC according to the expression levels of MPP7 in TCGA-KIRC cohort.
Characteristics | Low MPP7 | High MPP7 | P value |
---|---|---|---|
Sample size | 269 | 270 | – |
T stage, n (%) | <0.001 | ||
T1 | 118 (43.9) | 160 (59.3) | |
T2 | 33 (12.3) | 38 (14.1) | |
T3 | 110 (40.9) | 69 (25.6) | |
T4 | 8 (3.0) | 3 (1.1) | |
N stage, n (%) | 0.160 | ||
N0 | 114 (42.4) | 127 (47.0) | |
N1 | 11 (4.1) | 5 (1.9) | |
M stage, n (%) | <0.001 | ||
M0 | 196 (72.9) | 232 (85.9) | |
M1 | 56 (20.8) | 22 (8.1) | |
Pathologic stage, n (%) | <0.001 | ||
Stage I | 114 (42.4) | 158 (58.5) | |
Stage II | 25 (9.3) | 34 (12.6) | |
Stage III | 70 (26.0) | 53 (19.6) | |
Stage IV | 59 (21.9) | 23 (8.5) | |
Histologic grade, n (%) | <0.001 | ||
G1 | 7 (2.6) | 7 (2.6) | |
G2 | 101 (37.5) | 134 (49.6) | |
G3 | 104 (38.7) | 103 (38.1) | |
G4 | 55 (20.4) | 20 (7.4) | |
Gender, n (%) | 0.547 | ||
Female | 89 (33.1) | 97 (35.9) | |
Male | 180 (66.9) | 173 (64.1) | |
Age (years), n (%) | 0.636 | ||
≤60 | 131 (48.7) | 138 (51.1) | |
>60 | 138 (51.3) | 132 (48.9) |
ccRCC, clear cell renal cell carcinoma; MPP7, membrane palmitoylated protein-7; TCGA, The Cancer Genome Atlas; KIRC, kidney renal clear cell carcinoma.