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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: Eur J Cell Biol. 2022 Mar 9;101(2):151214. doi: 10.1016/j.ejcb.2022.151214

Fig. 6.

Fig. 6.

HS1-KO neutrophils show defects in actin polymerization and cell stiffness. (A) Normalized MFI of F-actin as determined by AF488-phalloidin staining in blood neutrophils from WT and HS1-KO mice after treatment with CXCL1 for the indicated times; n = 6. (B) Normalized MFI of F-actin in HoxB8 neutrophils after treatment with CXCL1 for the indicated times; n = 4. Data are displayed as mean ± SEM; *p < 0.05, **p < 0.01, ***p < 0.001. (C) Kaplan-Meier curves of neutrophil fractions that transited the 5 μm microfluidics device at the indicated times. The hazard ratio for WT/HS1-KO is 0.7769 [95% CI 0.6515–0.9266; p-value < 0.0001].