Table 1.
Clinical and radiological parameters in the subgroups of pneumonia severity, as assessed by AI.
| Characteristics | AI pneumonia severity group | ||
|---|---|---|---|
| Mild | Moderate | Critical | |
| Number | 33 | 73 | 274 |
| Age, yr | 64.2 (14.4)C | 65.0 (11.2)C | 59.1 (12.7)M,Mo |
| Female, n (%) | 12 (36.4%) | 29 (39.7%) | 104 (37.9%) |
| Radiological parameters | |||
| AIV, cm³ | 45.78 (13.62–94.42)Mo,C | 333.42 (231.40-540.48)M,C | 1130.43 (686.28-1708.29)M,Mo |
| AGV, cm³ | 41.93 (12.75–89.86)Mo,C | 289.43 (182.16-455.61)M,C | 879.63 (523.38-1317.99)M,Mo |
| ACV, cm³ | 2.73 (0.94–9.19)Mo,C | 36.41 (25.19–73.83)M,C | 196.19 (123.43-329.54)M,Mo |
| PIV, % | 1.00 (0.38–1.91)Mo,C | 7.30 (5.04–10.53)M,C | 27.90 (18.28–43.13)M,Mo |
| PGV, % | 0.77 (0.37–1.68)Mo,C | 6.53 (3.91–9.57)M,C | 22.30 (14.75–35.09)M,Mo |
| PCV, % | 0.05 (0.01–0.20)Mo,C | 0.84 (0.51–1.55)M,C | 5.28 (3.01–9.51)M,Mo |
| Parameters on admission | |||
| Respiratory rate, /min | 16 (14–18) | 16 (13–18) | 16 (15–18) |
| Oxygen saturation, % | 96 (91–97)C | 94 (89–95)C | 89 (85–92)M,Mo |
| CRP, mg/l | 38.7 (16.9–69.4)C | 47.1 (22.9–88.9)C | 82.5 (47.4–139)M,Mo |
| IL6, pg/ml | 16.7 (11.2–46.2) | 29.5 (12.2–55.9) | 39.5 (13.9–69.8) |
| IG, 10^3/µl | 0.02 (0.01–0.05) | 0.03 (0.02–0.04) | 0.03 (0.02–0.06) |
| WBC, 10^3/µl | 4.92 (4.09–7.52) | 5.70 (3.93–6.93) | 5.67 (4.43–8.07) |
| Neutrophil count, 10^3/µl | 3.29 (2.42–5.02) | 3.84 (2.51–5.84) | 4.48 (3.16–6.83) |
| Lymphocyte count, 10^3/µl | 1.01 (0.73–1.35)C | 0.87 (0.64–1.17) | 0.73 (0.58–1.05)M |
| Ferritin, µg/l | 498 (235–995) | 531 (253–878)C | 814 (517–1325)Mo |
| LDH, U/l | 275 (232–353)C | 289 (237–359)C | 386 (316–519)M,Mo |
| NIH score, 0–4 | 2 (1–2)C | 2 (2–3)C | 3 (2–3)M,Mo |
| Clinical course | |||
| In hospital death, n (%) | 0 | 7 (9.6%) | 22 (8.0%) |
| Transfer to the ICU, n (%) | 0 | 5 (6.8%) | 27 (9.9%) |
| Length of hospital stay, days | 14 (10–21)Mo | 10 (8–15)M,C | 12 (9–17)Mo |
Data shown as mean (SD), median (interquartile range), number (%)
M significantly (p < 0.05) different from Mild group
Mo significantly (p < 0.05) different from Moderate group
C significantly (p < 0.05) different from Critical group
AI – artificial intelligence, AIV - absolute inflammation volume, AGV - absolute ground glass volume, ACV - absolute consolidation volume, PIV - percentage inflammation volume, PGV - percentage ground glass volume, PCV - percentage consolidation volume, CRP - C-reactive protein, IL6 - interleukin 6, IG – immature granulocytes, WBC – white blood cells, LDH – lactate dehydrogenase, NIH score – National Institute of Health severity score, ICU - intensive care unit, SD - standard deviation