Table 2.
Clinical and radiological parameters in the subgroups of pneumonia severity, as assessed clinically
| Characteristics | NIH severity group | ||
|---|---|---|---|
| Asymptomatic or mild | Moderate | Severe or critical | |
| Number | 46 | 127 | 215 |
| Age, yr | 64.8 (14.4) | 59.4 (13.3) | 60.2 (12.3) |
| Female, n (%) | 19 (41.3%) | 49 (38.6%) | 78 (36.3%) |
| Radiological parameters | |||
| AIV, cm³ | 282.98 (37.44-478.98)Mo,Se | 568.96 (255.72-1011.46)As,Se | 1145.98 (620.62-1796.24)As,Mo |
| AGV, cm³ | 221.92 (33.27–428.60) Mo,Se | 477.59 (197.59-812.99) As,Se | 893.51 (484.91-1354.22) As,Mo |
| ACV, cm³ | 37.45 (4.17–124.80) Se | 95.13 (27.75-190.78) Se | 191.41 (100.93–348.10) As,Mo |
| PIV, % | 6.83 (0.61–13.53) Mo,Se | 14.47 (5.14–24.58) As,Se | 29.17 (16.48–45.97) As,Mo |
| PGV, % | 5.97 (0.60-11.03) Mo,Se | 11.58 (4.30–21.30) As,Se | 22.53 (13.07–37.45) As,Mo |
| PCV, % | 0.97 (0.06–2.52) Se | 2.25 (0.66–4.85) Se | 5.03 (2.45–9.88) As,Mo |
| Parameters on admission | |||
| Respiratory rate, /min | 16 (14–18) | 16 (14–18) Se | 17 (15–20) Mo |
| Oxygen saturation, % | 95 (93–97) Mo,Se | 93 (89–95) As,Se | 87 (82–90) As,Mo |
| CRP, mg/l | 29.5 (16.2–63.3) Mo,Se | 62.1 (35.3–97.6) As,Se | 94.5 (50.9–151.0) As,Mo |
| IL6, pg/ml | 28.4 (9.5–34.8) | 31.3 (12.2–62.5) | 35.8 (14.2–72.3) |
| IG, 10^3/µl | 0.02 (0.01–0.05) Se | 0.03 (0.02–0.05) | 0.04 (0.02–0.06) As |
| WBC, 10^3/µl | 5.48 (4.10–7.40) | 5.16 (4.15–6.88) | 5.92 (4.43–8.36) |
| Neutrophil count, 10^3/µl | 3.60 (2.75–5.24) | 3.80 (2.66–5.62) Se | 4.61 (3.24–7.23) Mo |
| Lymphocyte count, 10^3/µl | 0.92 (0.65–1.36) | 0.82 (0.63–1.14) | 0.72 (0.56–1.01) |
| Ferritin, µg/l | 406 (179–679) Se | 629 (377–1045) Se | 914 (551–1536) As,Mo |
| LDH, U/l | 268 (231–318) Mo,Se | 326 (271–401) As,Se | 394 (326–524) As,Mo |
| Clinical course | |||
| In hospital death, n (%) | 3 (6.5%) | 4 (3.1%) Se | 22 (10.2%) Mo |
| Transfer to the ICU, n (%) | 1 (2.2%) Se | 5 (3.9%) Se | 26 (12.1%) As, Mo |
| Length of hospital stay, days | 13 (10–20) Mo | 10 (8–14) As,Se | 13 (9–18) Mo |
Data shown as mean (SD), median (interquartile range), number (%)
As significantly (p < 0.05) different from Asymptomatic or mild group
Mo significantly (p < 0.05) different from Moderate group
Se significantly (p < 0.05) different from Severe or critical group
NIH severity – National Institute of Health severity, AIV - absolute inflammation volume, AGV - absolute ground glass volume, ACV - absolute consolidation volume, PIV - percentage inflammation volume, PGV - percentage ground glass volume, PCV - percentage consolidation volume, CRP - C-reactive protein, IL6 - interleukin 6, IG – immature granulocytes, WBC – white blood cells, LDH – lactate dehydrogenase, ICU - intensive care unit, SD - standard deviation