Table 1.
The ranking of best eight aptamers based on HADDOCK score and GA analysis, and their binding at lateral gate.
| Aptamer | HADDOCK score | HADDOCK score rank | Euclidean distance | GA rank | Binding at lateral gate |
|---|---|---|---|---|---|
| Apt31* | − 130.4 ± 26.4 | 1 | 68.103 | 60 | Yes |
| Apt47 | − 125.4 ± 22.7 | 2 | 29.061 | 3 | Yes |
| Apt66 | − 123.9 ± 7.5 | 3 | 52.157 | 30 | No |
| Apt62 | − 113.4 ± 17.6 | 4 | 63.369 | 50 | No |
| Apt91 | − 106.5 ± 5.5 | 5 | 47.512 | 16 | No |
| Apt69 | − 106.5 ± 13.1 | 6 | 24.273 | 2 | No |
| Apt33* | − 106.0 ± 4.7 | 7 | 19.960 | 1 | No |
| Apt32 | − 104.6 ± 6.1 | 8 | 66.443 | 58 | No |
*The top ranked aptamers under each ranking.