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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: Int J Hematol. 2022 Jul 1;116(2):174–181. doi: 10.1007/s12185-022-03404-x

Figure 4. Feedback loops involving GATA factor, genome, and small molecules control cellular differentiation.

Figure 4.

GATA factor dependent genome regulation controls the expression of transporters (SLCs) and biosynthetic enzymes for small molecules. The small molecules then function in a feedback loop to control GATA factor and genome function via protein effectors, e.g. BACH1.