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. 2023 May 9;23:161. doi: 10.1186/s12890-023-02465-w

Table 1.

Baseline patient and primary lesion characteristics

Patient characteristic Total
(N = 264)
Age at procedure, years 69.5 ± 10.5
Sex, female 150 (56.8%)
White 252 (95.5%)
Body mass index, kg/m2 (N = 263) 27.4 ± 6.9
Comorbidities/medical history
 Emphysema 114 (43.2%)
 Chronic obstructive pulmonary disease 136 (51.5%)
 Prior invasive lung procedure or surgery 29 (11.0%)
 History of lung cancer 29 (11.0%)
  Primary lung cancer 25 (86.2%)
  Metastatic lung cancer – solid tumor 4 (13.8%)
 History of extrathoracic malignancies 86 (32.6%)
 Family history of lung cancer 36 (13.6%)
 Family history of extrathoracic cancer 123 (46.6%)
Smoking status (N = 262)
 Prior smoker 125 (47.7%)
 Current smoker 72 (27.5%)
 Never smoked 65 (24.8%)
Number of pulmonary lesions visualized on pre-procedure CT scans 1 (1–22)
Pre-procedure probability of malignancya (N = 253) 60.2 ± 28.1%
Pre-procedure probability of malignancya ≥ 65% (N = 253) 122 (48.2%)
Primary lesion characteristic Total
(N = 264)
Lesion sizeb, mm 19.3 (3.2–72.5)
Lesion sizeb < 20 mm 137/264 (51.9%)
Location
 Proximal third 27/263 (10.3%)
 Middle 81/263 (30.8%)
 Peripheral (outer third of the lung) 155/263 (58.9%)
Distance from closest edge to pleurac, mm 12.0 (0.0–90.0)
Lesion lobe location
 Right upper lobe 82/264 (31.1%)
 Right middle lobe 17/264 (6.4%)
 Right lower lobe 52/264 (19.7%)
 Left upper lobe 79/264 (29.9%)
 Left lower lobe 34/264 (12.9%)
Visible bronchus leading to lung lesion 78/259 (30.1%)
Nodule type
 Solid 205/264 (77.7%)
 Subsolid 59/264 (22.4%)
  Pure ground glass (non-solid) 13 (22.0%)
  Semi-solid 46 (78.0%)
Margin specifications
 Spiculated 112/253 (44.3%)
 Smooth 92/253 (36.4%)
 Lobulated 49/253 (19.4%)
Calcification 11/264 (4.2%)

Results are displayed as n (%), mean ± standard deviation, or median (minimum–maximum)

CT Computed tomography

aCalculated using an adapted Mayo Clinic model

bSize was calculated as the mean of the long and short axes dimensions when both were reported and as the long axis dimension otherwise

cBased on 210 non-missing values