Table 5.

HTR1A and TPH2 haplotype frequencies and the association with LPE risk

Gene	SNPs	Haplotype	Freq (case)	Freq (control)	OR (95% CI)	p-value
HTR1A	rs878567|rs6294	GA	0.181	0.184	0.98(0.63–1.52)	0.938
		AT	0.181	0.184	0.98(0.63–1.52)	0.938
TPH2	rs10879346|rs1386492	AT	0.434	0.367	1.33(0.95–1.86)	0.093
		GC	0.407	0.429	0.91(0.66–1.27)	0.585
		AC	0.159	0.204	0.74(0.48–1.15)	0.179
	rs11179023|rs7305115	GT	0.440	0.384	1.28(0.91–1.79)	0.160
		AC	0.170	0.200	0.81(0.53–1.26)	0.351
		GC	0.390	0.416	0.90(0.65–1.25)	0.533
	rs11179041|rs10879352	AT	0.198	0.209	0.93(0.62–1.40)	0.737
		CC	0.198	0.224	0.86(0.58–1.28)	0.451
		GT	0.049	0.106	0.44(0.22–0.90)	0.024 *

Block comprised of the three closely linked SNPs rs9303628 and rs2054847; ORs: odds ratio, 95% CI: 95% confidence intervals;

^* Bold values indicate statistical significance (p < 0.05)