Table 2.
# Events/total N | Median rwPFS (95% CI) | 6-month % PFS | 12- month % PFS |
HR (95% CI) * | |
---|---|---|---|---|---|
Entire cohort | 1423/1746 | 3.0 (2.8–3.1) | 30.0 | 17.3 | – |
Mutation type | |||||
EGFR | 406/458 | 2.5 (2.3–2.6) | 17.8 | 8.1 | Reference |
ALK | 58/65 | 2.3 (1.6–3.1) | 24.1 | 11.2 | 0.89 (0.67–1.17) |
BRAF | 115/146 | 3.6 (2.6–4.7) | 36.2 | 20.6 | 0.74 (0.59–0.91) |
KRAS | 844/1077 | 3.3 (3.0–3.6) | 34.7 | 21.1 | 0.75 (0.66–0.85) |
rwPFS Real-world progression free survival, CI confidence interval, HR hazard ratio
Cox regression model adjusted for sex, age, and line of therapy checkpoint inhibitor given