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. Author manuscript; available in PMC: 2023 May 10.
Published in final edited form as: J Cancer Res Clin Oncol. 2022 Jun 16;149(5):1755–1763. doi: 10.1007/s00432-022-04089-9

Table 2.

Real-world progression free survival (months) by oncogenic mutation type (N = 1746)

# Events/total N Median rwPFS (95% CI) 6-month % PFS 12-
month %
PFS
HR (95% CI) *
Entire cohort 1423/1746 3.0 (2.8–3.1) 30.0 17.3
Mutation type
 EGFR 406/458 2.5 (2.3–2.6) 17.8 8.1 Reference
 ALK 58/65 2.3 (1.6–3.1) 24.1 11.2 0.89 (0.67–1.17)
 BRAF 115/146 3.6 (2.6–4.7) 36.2 20.6 0.74 (0.59–0.91)
 KRAS 844/1077 3.3 (3.0–3.6) 34.7 21.1 0.75 (0.66–0.85)

rwPFS Real-world progression free survival, CI confidence interval, HR hazard ratio

*

Cox regression model adjusted for sex, age, and line of therapy checkpoint inhibitor given