Table 1.
Clinical characteristics of children with metabolic epilepsy
| Variables | No. of patients (%) |
|---|---|
| Total no. of patients | 63 |
| Gender distribution | |
| Males | 36 (57.1) |
| Females | 27 (42.9) |
| Age of onset (months) | |
| 0-12 | 47 (74.6) |
| >12 | 16 (25.4) |
| Age at diagnosis (months) | |
| 0-12 | 32 (50.8) |
| 13-24 | 11 (17.5) |
| >24 | 20 (31.7) |
| H/O Consanguinity | 47 (74.6) |
| Seizure type | |
| Focal clonic seizures | 15 (23.8) |
| Generalised onset–motor | |
| Tonic clonic | 46 (73) |
| Myoclonic | 12 (19) |
| Epileptic spasms | 7 (11.1) |
| Multiple types | 20 (31.7) |
| Multiple episodes prior to specific therapy | 43 (68.3) |
| Status epilepticus | 7 (11.1) |
| Developmental delay | 37 (58.7) |
| Developmental regression | 20 (31.7) |
| Diagnosis confirmed by | |
| Biochemical including enzyme assay | 42 (66.7) |
| Genetic testing | 14 (22.2) |
| Therapeutic trial | 4 (6.3) |
| Skin biopsy | 3 (4.8) |