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. 2023 May 10;18(5):e0284733. doi: 10.1371/journal.pone.0284733

Table 4. Estimated number of deaths that could be averted or delayed if Canadians were to meet the interim mean sodium intake target of 2,300 mg/day (corresponding to 5.75 g of salt/d) due to a systematic reduction of sodium levels in the Canadian food supply (scenario A)–presented by cause of death (95% UI).

Cause of death (ICD-10 Code) 1 Total n (95% UI) 2 % Men n (95% UI) 2 % Women n (95% UI) 2 %
Cardiovascular diseases 2176 (869, 3687) 100 1302 (508, 2228) 100 865 (331, 1443) 100
Ischaemic heart diseases (CHD) (I20-25) 975 (400, 1635) 44.8 659 (263, 1112) 50.6 312 (121, 512) 36.1
Cerebrovascular diseases (Stroke) (I60-69) 454 (182, 767) 20.9 244 (97, 417) 18.7 207 (81, 343) 23.9
Heart failure (I50) 247 (99, 427) 11.4 129 (50, 227) 9.9 115 (44, 200) 13.3
Aortic aneurysm (I71) 59 (23, 105) 2.7 40 (15, 70) 3.1 19 (7, 34) 2.2
Pulmonary embolism (I26) 12 (4, 26) 0.6 6 (2, 13) 0.5 6 (2, 12) 0.7
Rheumatic heart disease (I05-09) 10 (3, 22) 0.5 4 (1, 9) 0.3 6 (2, 13) 0.7
Hypertensive disease (I10-15) 413 (153, 750) 19.0 213 (77, 389) 16.4 197 (71, 348) 22.8
Total deaths prevented under age 75 795 (308, 1371) 36.5 585 (224, 1016) 44.9 205 (78, 343) 23.7
% of CVD deaths that could have been averted or delayed (reference year: 2019) 3 3.7% 4.2% 3.1%

1. WHO, International Statistical Classification of Diseases and Related Health Problems, Tenth Revision [70].

2. 95% UI are based on 10,000 iterations of Monte Carlo analysis.

3. Deaths in Canada (2019) attributable to the CVDs under study = 58,476 (men 30,663; women 27,813).

Note: total deaths averted or delayed represent less than the sum of its components, given that double counting has been accounted for in PRIME during the modelling process.