Table 1.
Systematic review | Population | Study designs included / | # of databases searched | Meta-analysis (yes/no) sample size | ROB tool | Certainty of evidence (yes/no) | Outcomes of interest reported |
---|---|---|---|---|---|---|---|
Mohr et al. 2022 [32••] | Adults with dyslipidemia (n = 838) | RCTs (n = 8) |
4 (MEDLINE, CINAHL, Cochrane CENTRAL, and Cochrane Database of Systematic Reviews) |
Yes | Cochrane’s ROB 2.0 | Yes | Total-C, LDL-C, HDL-C, TG, BP |
Ross et al. 2019 [34••] |
Adults (≥ 18 years) at high-risk of cardiovascular disease (n = 1530) |
RCTs (n = 10) |
7 (ProQuest Family Health, Scopus, PubMed Central, MEDLINE, CINAHL and Cochrane) |
Yes | Cochrane’s ROB | Yes | Total-C, LDL-C, HDL-C, TG |
Sikand et al. 2018 [33••] |
Adults with dyslipidemia and cardiovascular risk factors (n = 5704) |
RCTs(n = 11) Total studies (n = 34) • RCTs deemed observational per research question4 • Randomized cohort studies1 • Non-randomized controlled trials2 • Non-controlled trials2 • Prospective cohorts2 • Retrospective cohorts2 • Pre-Post studies10 |
3 (PubMed, Medline, Worldcat.org) |
Yes | Academy’s Quality Criteria Checklist | Yes | Total-C, LDL-C, HDL-C, TG, BP, FBG, A1c, BMI |
A1c, glycosylated hemoglobin; BMI, body mass index; BP, blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; RCTs, randomized controlled trials; ROB, risk of bias; SBP, systolic blood pressure; TG, triglyceride; Total-C, total cholesterol