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. 2023 May 11;25(6):331–342. doi: 10.1007/s11883-023-01096-0

Table 1.

Recent systematic reviews examining the effect of medical nutrition therapy in the management of adults with dyslipidemia

Systematic review Population Study designs included / # of databases searched Meta-analysis (yes/no) sample size ROB tool Certainty of evidence (yes/no) Outcomes of interest reported
Mohr et al. 2022 [32••] Adults with dyslipidemia (n = 838) RCTs (n = 8)

4

(MEDLINE, CINAHL, Cochrane CENTRAL, and Cochrane Database of Systematic Reviews)

Yes Cochrane’s ROB 2.0 Yes Total-C, LDL-C, HDL-C, TG, BP
Ross et al. 2019 [34••]

Adults (≥ 18 years) at high-risk of cardiovascular disease

(n = 1530)

RCTs (n = 10)

7

(ProQuest Family Health, Scopus, PubMed Central, MEDLINE, CINAHL and Cochrane)

Yes Cochrane’s ROB Yes Total-C, LDL-C, HDL-C, TG
Sikand et al. 2018 [33••]

Adults with dyslipidemia and cardiovascular risk factors

(n = 5704)

RCTs(n = 11)

Total studies (n = 34)

• RCTs deemed observational per research question4

• Randomized cohort studies1

• Non-randomized controlled trials2

• Non-controlled trials2

• Prospective cohorts2

• Retrospective cohorts2

• Pre-Post studies10

3

(PubMed, Medline, Worldcat.org)

Yes Academy’s Quality Criteria Checklist Yes Total-C, LDL-C, HDL-C, TG, BP, FBG, A1c, BMI

A1c, glycosylated hemoglobin; BMI, body mass index; BP, blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; RCTs, randomized controlled trials; ROB, risk of bias; SBP, systolic blood pressure; TG, triglyceride; Total-C, total cholesterol