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. 2023 Apr 26;13:1094040. doi: 10.3389/fonc.2023.1094040

Table 1.

Clinical and pathological factors in different mean platelet volume.

Variables n (%) Total (n = 879) Low MPV (n = 445) High MPV (n = 434) P value
Age(year) 0.292
 ≤ 65 553 (62.9) 288 (64.7) 265 (61.1)
 >65 326 (37.1) 157 (35.3) 169 (38.9)
Gender < 0.001
 Male 732 (83.3) 390 (87.6) 342 (78.8)
 Female 147 (16.7) 55 (12.4) 92 (21.2)
KPS 0.465
 90 -100 580 (66.0) 288 (64.7) 292 (67.3)
 70 - 80 299 (34.0) 157 (35.3) 142 (32.7)
Number of LN resection 0.155
 ≤1 5 220 (25.0) 121 (27.2) 99 (22.8)
 >15 659 (75.0) 324 (72.8) 335 (77.2)
Differentiation 0.774
 High 142 (16.2) 70 (15.7) 72 (16.6)
 Middle 368 (41.9) 183 (41.1) 185 (42.6)
 Poor 369 (42.0) 192 (43.1) 177 (40.8)
Location 0.568
 Upper 272 (30.9) 139 (31.2) 133 (30.6)
 Middle 436 (49.6) 214 (48.1) 222 (51.2)
 Lower 171 (19.5) 92 (20.7) 79 (18.2)
Lymphovascular invasion 0.027
 Yes 199 (22.6) 115 (25.8) 84 (19.4)
 No 680 (77.4) 330 (74.2) 350 (80.6)
Neural invasion 0.901
 Yes 197 (22.4) 101 (22.7) 96 (22.1)
 No 682 (77.6) 344 (77.3) 338 (77.9)
Path T stage 0.325
 T1 42 (4.8) 22 (4.9) 20 (4.6)
 T2 149 (17.0) 72 (16.2) 77 (17.7)
 T3 566 (64.4) 280 (62.9) 286 (65.9)
 T4a 122 (13.9) 71 (16) 51 (11.8)
Path N stage 0.039
 N0 39 (4.4) 17 (3.8) 22 (5.1)
 N1 460 (52.3) 219 (49.2) 241 (55.5)
 N2 265 (30.1) 138 (31) 127 (29.3)
 N3 115 (13.1) 71 (16) 44 (10.1)
Treatment 0.333
 SA 632 (71.9) 313 (70.3) 319 (73.5)
 SA+POCRT 247 (28.1) 132 (29.7) 115 (26.5)

MPV, mean platelet volume; KPS, Karnofsky performance score; LN, lymph node; Path, pathology; TNM, Tumor Nodes Metastasis; SA, surgery alone; POCRT, postoperative chemoradiotherapy.