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. 2023 May 3;38(13):959–973. doi: 10.1089/ars.2022.0058

FIG. 5.

FIG. 5.

Adoptive transfer of Keap1-KO CD4+ T cells resulted in functional protection from IRI. (A) Plasma creatinine concentrations were significantly lower in recipient mice of Keap1-KO CD4+ T cells compared with recipients of control CD4+ T cells at 24 h. (B) Proportions of necrotic tubules and representative images of H&E-stained kidney sections of each experimental group. Original magnification × 200; n in experimental groups at 24 h: Control CD4+ T cells: 12; Keap1-KO CD4+ T cells: 10; n in experimental groups at 72 h: control CD4+ T cells: 8; Keap1-KO CD4+ T cells: 6 (three independent experiments). Statistical analysis was performed using paired, two-tailed T-test; *p < 0.05. H&E, hematoxylin and eosin; IRI, ischemia-reperfusion injury.