Table 1. Consensus guidelines for managing DME.

Consensus	Supporting data
Treatment goal	RISE/RIDE (2012)[21]
	MEAD (2014)[22]
	RESTORE (2011)[20]
	VIVID/VISTA (2014)[23]
	DRCR.net Protocol I (2010)[24]
	DRCR.net Protocol T (2015) [25]
DME treatment options
Anti-vascular endothelial growth factor	RESTORE (2011)[20]
	Robert & Gabriel (2016)[28]
	Curry et al (2020)[26]
	Zabrin et al (2017)[29]
	DRCR.net Protocol T (2015)[25]
	Ademan & Garg (2017)[27]
	Jain et al (2017)[30]
Steroid implant	MAED (2014)[21]
	Bucolo et al (2018)[31]
Focal/grid laser	EURETINA (2017)[1]
	Ademan & Garg (2017)[27]
	Pai et al (2010)[32]
Pars plana vitrectomy + membrane peeling	Gary et al (2017)[33]
Special conditions
Blood sugar control	Mathew et al (2015)[34]
	Rajalakshmi et al (2016)[35]
Cataract surgery	Chhablani et al (2020)[36]
Treatment in pregnant DME patients	Peracha et al (2015)[37]
	Rosenthal & Johnson (2018)[38]
	Mathew et al (2015)[34]
	Yoo et al (2016)[39]
Vitrectomized eyes	Chhablani et al (2020)[36]
	Medeiros et al (2014)[40]
Stable pre-existing glaucoma	Chhablani et al (2020)[36]
	Lakhani et al (2020)[41]
Endophthalmitis	Pai et al (2010)[32]
	McCannel (2011)[42]
	Kiss et al (2018)[43]
	Goel (2017)[44]
Treatment algorithm for DME	Chhablani et al (2020)[36]

DME: Diabetic macular edema.