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. 2023 May 10;617(7960):312–324. doi: 10.1038/s41586-023-05896-x

Fig. 5. Visualizing complex pangenome loci.

Fig. 5

ac, Structural haplotypes of RHD and RHCE from the MC graph. Locations of RHD and RHCE within the graph (a). The colour gradient is based on the precise relative position of each gene; green, head of a gene; blue, end of a gene. The lines alongside the graph are based on the approximate position of gene bodies, including exons and transcription start sites. Different structural haplotypes take different paths through the graph (b). The colour gradient and lines show the path of each allele; red, start of a path; blue, end of a path. Frequency and linear structural visualization of all structural haplotypes called by the graph among 90 haploid assemblies (c). Asterisks indicate newly discovered haplotypes. df, Structural haplotypes of HLA-A from the PGGB graph, visualized using the same conventions as ac. del, deletion; ins, insertion; inv, inversion.