TABLE 1.

Inclusion and exclusion criteria for the literature review

Step	Inclusion criteria	Exclusion criteria
First step: Title and abstract	Published in 1985 or later	–
	Published in English or German
	Examining the effect of different doses of chemotherapeutics in human beings
Second step: Full text	At least one conversion factor for converting the dose of a substance into the dose of another one was explicitly stated in the paper or was deductible from the doses of the respective substances.	Generally assuming equality of effect (factor = 1) without presenting supporting evidence
	The respective doses were intended for the same mode of application	Article only referenced a factor from another earlier publication unchanged and the factor could be verified in the referenced paper (except for literature reviews resulting in a definitive factor)