Table 3.
HRV time–domain parameters by OSA status in a cohort with atrial fibrillation
| All patients | No OSA AHI < 5/h | OSA AHI > 5/h | p value | p value (adjusted for age, sex, BMI) | |
|---|---|---|---|---|---|
| n = 89 | n = 35 | n = 54 | |||
| Average NN interval (ms) | |||||
| Non-REM | 1080.2 ± 162.9 | 1062.0 ± 133.9 | 1091.9 ± 179.4 | 0.401 | 0.475 |
| REM | 1067.2 ± 166.4 | 1041.2 ± 136.7 | 1084.3 ± 182.5 | 0.243 | 0.492 |
| †RMSSD (ms) | |||||
| Non-REM | 28.7 (23.1) | 27.3 (20.7) | 30.9 (23.6) | 0.447 | 0.570 |
| REM | 26.7 (22.7) | 20.4 (20.8) | 25.3 (23.5) | 0.376 | 0.374 |
| †pNN50 (%) | |||||
| Non-REM | 5.5 (14.7) | 4.5 (12.2) | 6.2 (15.9) | 0.063 | 0.061 |
| REM | 2.8 (12.3) | 1.9 (11.1) | 3.3 (17.2) | 0.772 | 0.631 |
| Triangular index (nu) | |||||
| Non-REM | 10.8 ± 4.3 | 10.7 ± 4.4 | 10.8 ± 4.4 | 0.975 | 0.612 |
| REM | 11.7 ± 4.6 | 11.7 ± 4.6 | 11.6 ± 4.7 | 0.885 | 0.541 |
Data are presented as mean ± SD or median (IQR). Natural log-transformed data are indicated by †
Non-REM non-rapid eye movement, REM rapid eye movement, average NN interval average of N wave to N wave variation, RMSSD square root of the mean squared differences of successive NN intervals, pNN50 percentage of successive NN intervals that differ by more than 50 ms, triangular index: integral of the density of the RR interval histogram divided by its height